LOCI ORTHOPAEDICS LIMITED

Projekt → Modelling trajectories and mechanisms of childhood hip dysplasia With 40 million patients in Europe, osteoarthritis (OA) is the most common chronic and disabling disease. OA is incurable, and sy… Beitrag ansehen → Projekt → Multimodal Brain Imaging – Gene Relationships in Alzheimer Disease: Risk and Resilience The list of genes contributing to increased risk of developing Alzheimer’s Disease (AD) grows every year. To date, large case-con… Beitrag ansehen → Projekt → Role of Mitochondria-Associated ER membranes on microglia activation: implications for Alzheimer's disease. Alzheimer’s disease (AD) is an irreversible neurodegenerative condition affecting 50 million people worldwide. Despite intense re… Beitrag ansehen → Projekt → Sub-chromosomal regulation of mitotic transcription inhibition Chromosome condensation during mitosis has long been assumed to render mitotic chromatin incompatible with transcription. However… Beitrag ansehen → Projekt → Structural variants impacting peripheral neurodegeneration Many Mendelian diseases have benefited from next-generation sequencing (NGS) technologies for gene discovery and the establishmen… Beitrag ansehen → Projekt → Dissecting the molecular mechanisms of transgenerational epigenetic inheritance Small RNAs have a remarkable regulatory role in most eukaryotes. These molecules bind to Argonaute proteins (AGO) and form a comp… Beitrag ansehen →